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Periodontal research laboratory

Alejandra Chaparro

chaparro.ale@gmail.com

Department of periodontics, oral pathology and conservative dentistry

University of the Andes

Summary of your main research area in EVs

EVs as diagnostic tools.

List the 5 most recent publications

Exploring the Expression of Pro-Inflammatory and Hypoxia Related MicroRNA-20a, MicroRNA-30e, and MicroRNA-93 in Periodontitis and Gingival Mesenchymal Stem Cells under Hypoxia. Chaparro A.; Lozano, M.; Gaedechens, D.; López, C.; Albers, D.; Hernández, M.; Pascual, A.; Nart, J.; Irarrazabal, C.E. Int. J. Mol. Sci. 2022, 23,10310.https://doi.org/10.3390/ijms231810310. - Molecular Biomarkers in Peri-Implant Health and Disease: A Cross-Sectional Pilot Study. Chaparro A.; Beltrán, V.; Betancur, D.; Sam, Y.-H.; Moaven, H.; Tarjomani, A.; Donos, N.; Sousa, V. Int. J. Mol. Sci. 2022, 23, 9802. https://doi.org/. Periodontitis and Gestational Diabetes Mellitus: A Potential Inflammatory Vicious Cycle. Bendek MJ, Canedo-Marroquín G, Realini O, Retamal IN, Hernández M, Hoare A, Busso D, Monteiro LJ, Illanes SE, Chaparro A. Int J Mol Sci. 2021 Oct 31;22(21):11831. doi: 10.3390/ijms222111831. PMID: 34769262; PMCID: PMC8584134. Molecular signatures of extracellular vesicles in oral fluids of periodontitis patients. Alejandra Chaparro Padilla , Laura Weber Aracena , Ornella Realini Fuentes , Daniela Albers Busquetts , Marcela Hernández Ríos , Valeria Ramírez Lobos , Andrés Pascual La Rocca, José Nart Molina , Victor Beltrán Varas , Stephanie Acuña-Gallardo , Antonio Sanz Ruiz. Oral Dis. 2020 Mar 31. doi: 10.1111/odi.13338. Diagnostic potential of peri-implant crevicular fluid microRNA-21-3p and microRNA-150-5p and extracellular vesicles in peri-implant diseases. Chaparro A, Atria P, Realini O, Monteiro LJ, Betancur D, Acuña-Gallardo S, Ramírez V, Bendek MJ, Pascual A, Nart J, Beltrán V, Sanz A. J Periodontol. 2020 Nov 13. doi: 10.1002/JPER.20-0372. Online ahead of print. Oral extracellular vesicles in early pregnancy can identify patients at risk of developing gestational diabetes mellitus. Monteiro LJ, Varas-Godoy M, Monckeberg M, Realini O, Hernández M, Rice G, Romero R, Saavedra JF, Illanes SE, Chaparro A. PLoS One. 2019 Jun 26; 14 (6): e0218616. doi: 10.1371/journal.pone.0218616. eCollection 2019. PubMed PMID: 31242249; PubMed Central PMCID: PMC6594608.