Laboratory on Thymus Research

Dumith Chequer Bou-Habib

dumith.chequer@gmail.com

Oswaldo Cruz Institute

Fiocruz

EVs research

EVs in host and infectious agents (viruses, parasites, fungi, and bacteria).

Recent publications

1- Characterization and internalization of small extracellular vesicles released by human primary macrophages derived from circulating monocytes; Plos One, 2020; https:// doi.org/10.1371/journal.pone.0237795.

2- The Role of Extracellular Vesicles from Human Macrophages on Host-Pathogen Interaction; IJMS, 2021); https://doi.org/10.3390/ ijms221910262

3- Neutrophil extracellular traps from healthy donors and HIV 1 infected individuals restrict HIV 1 production in macrophages; Sci Rep 2020; https://doi.org/10.1038/s41598-020-75357-2

4- Neutrophil extracellular trap enriched supernatants carry microRNAs able to modulate TNF-α production by macrophages; Sci Rep 2020; https://doi.org/10.1038/s41598-020-59486-2

5- SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes, Cell Death Discovery, 2021; https://doi.org/10.1038/s41420-021-00428-w