Laboratory of Immunoparasitology and Flow Cytometry Core Facility

Alvaro Luiz Bertho

alvaro.bertho@ioc.fiocruz.br

Oswaldo Cruz Institute

FIOCRUZ

EVs research

EVs in host and infectious agents (viruses, parasites, fungi, and bacteria).

Recent publications

1- A New Strategy for Mapping Epitopes of LACK and PEPCK Proteins of Leishmania amazonensis Specific for Major Histocompatibility Complex Class I. Ferreira-Sena EP et al. Int J Mol Sci. 2023 Mar 22;24(6):5972. doi:10.3390/ijms24065972.

2- Carajurin Induces Apoptosis in Leishmania amazonensis Promastigotes through Reactive Oxygen Species Production and Mitochondrial Dysfunction. Silva-Silva JV et al Pharmaceuticals (Basel). 2022 9;15(3):331. doi: 10.3390/ph15030331.

3- Critically ill Coronavirus Disease Patients Exhibit Hyperactive Cytokine Responses Associated With Effector Exhausted Senescent T Cells in Acute Infection. Arcanjo A et al J Infect Dis. 2021 doi:10.1093/infdis/jiab425.

4- Flow-Cytometric Method for Viability Analysis of Mycoplasma gallisepticum and other Cell-Culture-Contaminant Mollicutes. Lawson-Ferreira R et al Curr Microbiol. 2021 doi: 10.1007/s00284-020-02255-1.

5- Contribution of Leishmania braziliensis antigen-specific CD4+ T, CD8+ T, NK and CD3+CD56+NKT cells in the immunopathogenesis of cutaneous leishmaniasis patients: Cytotoxic, activation and exhaustion profiles. Cunha CF et al PLoS One. 2020 doi: 10.1371/journal.pone.0229400