Extracellular metabolism of nucleotides

Cora Lilia Alvarez

alvarezcora@gmail.com

Institute of Biological Chemistry and Physicochemistry

National Scientific and Technical Research Council (CONICET)

EVs research

EVs in host and infectious agents (viruses, parasites, fungi, and bacteria).

Recent publications

1. In silico guided drug repurposing: discovery of new competitive and noncompetitive inhibitors of falcipain-2. Lucas N. Alberca, Sara R. Chuguransky, Cora L. Alvarez, Alan Talevi3 and Emir Salas-Sarduy. Front. Chem. | doi: 10.3389/fchem.2019.00534.

2. Regulation of extracellular ATP of human erythrocytes treated with alpha-hemolysin. Effects of cell volume, morphology, rheology and hemolysis” María F Leal Denis; Sophie D Lefevre; Cora L Alvarez; Natalia Lauri; Nicolás Enrique; Debora E Rinaldi; Rodolfo Gonzalez-Lebrero; Leandro E Vecchio; María V Espelt; Pablo Stringa; Carlos Muñoz-Garay; Verónica Milesi; Mariano A Ostuni; Vanesa Herlax; Pablo Schwarzbaum. BBA- Molecular Cell Research; doi.org/10.1016/j.bbamcr.2019.01.018

3. ATPe Dynamics in Protozoan Parasites. Adapt or Perish” Natalia Lauri, Zaher Bazzi, Cora L. Alvarez, María F. Leal Denis, Julieta Schachter, Vanesa Herlax, Mariano A. Ostuni, and Pablo J. Schwarzbaum. Genes 2019, 10(1), 16; https://doi.org/10.3390/genes10010016.

4. ATP release, PPIX transport and cholesterol uptake by human red blood cell are differently induced by a new family of TSPO ligands” I Marginedas-Freixa, CL Alvarez, M Moras, C Hattab, G Bouyer, A Chene, SD Lefevre, C Le Van Kim, F Bihel, PJ Schwarzbaum, MA Ostuni. International Journal of Molecular Sciences, 2018. Aceptado 6/10/2018. –

5. Human erythrocytes release ATP by a novel pathway involving VDAC oligomerization independent of pannexin-1”. I Marginedas-Freixa, CL Alvarez, M Moras, MF Leal Denis, C Hattab, F Halle, F Bihel, I Mouro-Chanteloup, SD Lefevre, C Le Van Kim, PJ Schwarzbaum, MA Ostuni. Scientific Reports, 2018. Doi: 10.1038/s41598-018-29885-7.