Cancer Cell Biology Lab

Manuel Varas-Godoy

manuel.varas@uss.cl

Center for Cellular Biology and Biomedicine

San Sebastian University

Summary of your main research area in EVs

EVs in cancer, inflammatory and neurological diseases.

List the 5 most recent publications

https://scholar.google.es/citations?user=4cZPsgkAAAAJ&hl=en 1. Vera N, Acuña-Gallardo S, Grünenwald F, Caceres-Verschae A, Realini O, Acuña R, Lladser A, Illanes SE, Varas-Godoy M†. “Small extracellular vesicles released from ovarian cancer stem-like cells in response to cisplatin promote the pro-tumorigenic activity of mesenchymal stem cells”. International Journal of Molecular Science (2019) 2. Lara P, Palma S, Salas-Huenuleo E, Polakovicova I, Guerrero S, Lobos-Gonzalez L, Campos A, Muñoz L, Jorquera- Cordero C, Varas-Godoy M, Cancino J, Arias E, Villegas J, Cruz LJ, Albericio F, Araya E, Corvalan AH, Quest AFG, Kogan MJ. “Gold nanoparticle based double-labelling of melanoma extracellular vesicles to determine specificity of uptake by cells and preferential accumulation in small metastatic tumors”. Journal of Nanobiotechnology (2020) 3. Acuña R, Varas-Godoy M, Alfaro I, Berthoud V, Retamal M. “Connexin-46 Contained in Extracellular Vesicles Enhance Malignancy in Breast Cancer Cells”. Biomolecules (2020) 4. Torres VI, Barrera DP, Varas-Godoy M, Arancibia D, Inestrosa NC. “Selective surface and intraluminal localization of Wnt ligands on small extracellular vesicles released by HT-22 hippocampal neurons” Frontiers in Cell and Developmental Biology (2021) 5. Simon L, Sanhueza S, Gaete-Ramirez B, Varas-Godoy M†, Quest AF†. “Role of the pro-inflammatory tumor microenvironment in extracellular vesicle-mediated transfer of therapy resistance”. Frontiers in Oncology (2022)